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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NKX3-1
All Species:
23.33
Human Site:
S127
Identified Species:
42.78
UniProt:
Q99801
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99801
NP_006158.2
234
26350
S127
P
K
Q
P
Q
K
R
S
R
A
A
F
S
H
T
Chimpanzee
Pan troglodytes
XP_001159503
229
26021
S122
P
K
Q
P
Q
K
R
S
R
A
A
F
S
H
T
Rhesus Macaque
Macaca mulatta
XP_001106332
232
26111
S125
P
K
Q
P
Q
K
R
S
R
A
A
F
S
H
T
Dog
Lupus familis
XP_543240
206
23431
R100
K
Q
P
Q
K
R
S
R
A
A
F
S
H
T
Q
Cat
Felis silvestris
Mouse
Mus musculus
P97436
237
26806
S128
T
K
Q
P
Q
K
R
S
R
A
A
F
S
H
T
Rat
Rattus norvegicus
P23441
372
38536
R164
P
S
A
P
R
R
K
R
R
V
L
F
S
Q
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507333
521
57733
S414
T
Q
K
Q
P
K
R
S
R
A
A
F
S
H
T
Chicken
Gallus gallus
Q90788
294
33054
P122
R
Q
R
K
R
R
K
P
R
V
L
F
S
Q
A
Frog
Xenopus laevis
Q9W7E8
213
24704
A107
Q
Q
Q
K
R
S
R
A
A
F
S
H
S
Q
V
Zebra Danio
Brachydanio rerio
Q90481
269
30288
R128
D
S
G
K
K
R
K
R
R
V
L
F
S
K
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P22809
382
41975
S178
G
L
S
R
K
K
R
S
R
A
A
F
S
H
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9NLC2
299
33058
R153
S
M
S
Q
R
R
K
R
R
V
L
F
S
Q
A
Sea Urchin
Strong. purpuratus
Q26656
405
44721
T256
P
Q
K
K
K
K
K
T
R
T
V
F
S
R
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.1
91.4
58.9
N.A.
66.2
22.5
N.A.
33.7
28.2
44.4
23.7
N.A.
23.8
N.A.
25.4
25.4
Protein Similarity:
100
94
93.5
67.5
N.A.
73.4
33.5
N.A.
37.6
39.7
58.9
36.4
N.A.
37.4
N.A.
36.7
36.5
P-Site Identity:
100
100
100
6.6
N.A.
93.3
33.3
N.A.
66.6
20
20
20
N.A.
60
N.A.
20
33.3
P-Site Similarity:
100
100
100
26.6
N.A.
93.3
53.3
N.A.
80
53.3
46.6
40
N.A.
66.6
N.A.
40
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
0
8
16
54
47
0
0
0
39
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
8
85
0
0
0
% F
% Gly:
8
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
8
47
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
8
31
16
31
31
54
39
0
0
0
0
0
0
8
0
% K
% Leu:
0
8
0
0
0
0
0
0
0
0
31
0
0
0
0
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
39
0
8
39
8
0
0
8
0
0
0
0
0
0
0
% P
% Gln:
8
39
39
24
31
0
0
0
0
0
0
0
0
31
8
% Q
% Arg:
8
0
8
8
31
39
54
31
85
0
0
0
0
8
0
% R
% Ser:
8
16
16
0
0
8
8
47
0
0
8
8
93
0
8
% S
% Thr:
16
0
0
0
0
0
0
8
0
8
0
0
0
8
39
% T
% Val:
0
0
0
0
0
0
0
0
0
31
8
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _